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Biosensors
Technology Analyst: Rob Reid
Phone: +44-(0)20-8256-1400
Fax: +44-(0)20-8760-0635 |
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Viewpoints
About This Technology
Biosensors represent a powerful technology development in analytical measurement technology. Biosensors have the ability to measure constantly the presence, absence, or concentration of specific organic or inorganic substances and to do so accurately, with rapid response time, and ultimately at low cost. Their perceived advantages over existing technologies include the ability to monitor broad or narrow spectra of analytes continuously in real time and simply to allow decentralized analyte testing. Their perceived weakness is the instability of the biological molecules outside their natural environment, which results in a restricted shelf life.
Biosensors find commercial application in the areas of health care, food-quality control, pharmaceuticals, and environmental monitoring and greatest use in health care—especially in patient monitoring. A common requirement of all these applications is on-site analysis, preferably on a real-time basis. The resulting benefits of closer monitoring range from a more efficient industrial productions process to better-informed legislation on safety standards and population exposure to chemical and biological hazards. However, the market demand for biosensors in nonhealth applications will accelerate only when cheap and reliable biosensor technologies become available. The apparent opportunities in biosensor commercialization have led to interest by many large electronic and life science companies. However, without the technical skills, the delivery channels, or a unique, differentiated, biosensor offering, players will have great difficulty entering the market. Given the cost and complexity of biosensor development, a model of strategic cooperation is finding wide adoption. This model has been in use the longest in Japan; however, other countries are increasingly emulating it.
Bottlenecks in the technical development of biosensors include the difficulty of fabricating devices in bulk and the single- or restricted multiple-use nature of most biosensors currently available (leading to the need continuously to repurchase device components as well as consumables). In addition, the combination of electronic and biological components in a working device is currently difficult and expensive to achieve and requires significant class-discipline research. The high cost of biosensor development reduces the potential for biosensor use in low-cost applications. Because several competing technologies to biosensors exist (including dipstick tests and such laboratory techniques as spectrophotometry), the commercial success of biosensors hinges on their use in applications where they have a unique performance advantage such as simplicity of use, greater sensitivity, faster response time, or the ability to monitor an analyte continuously. Even in the largest markets (such as glucose monitoring) that biosensors can access, competition on price or technology alone is unlikely to form the basis of a successful strategy.
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